Case of the month - March 2007
History:
- 50 year old female - excision biopsy of 5mm focus of screen-detected DCIS
Medium power view (x 20) showing high grade DCIS with coarse luminal calcs
'Mouse over' for high power (x40) view

Low power overview (x 4) showing DCIS and calcs
'Mouse over' for detail (x4)

Labels 'A' show the site of a recent core biopsy
Inset shows a foreign body giant cell reaction related to this

High power view of image above.
'A' = foreign body giant cell reaction
'B' = needle biopsy reaction
'C' = focus of possible microinvasion

- What are the main features in this biopsy?
- Are there any additional stains that might help you with the diagnosis?
- What is your diagnosis?