Image of the Week (1)
Core biopsy of breast - sponge artefact
The criss-cross pattern seen on this H&E is due to the biopsy being placed on a sponge and allowed to dry before putting into formalin fixative.
The pattern imprints through the block and does not disappear on deeper sectioning.
'Mouse over' - for high power view
I am grateful to my colleague, Dr Marie O'Donnell, who pointed this out to me